Neurology experts are investigating why women are nearly twice as likely to develop Alzheimer’s disease compared to men. This topic came into focus after British TV host Fiona Phillips shared her experience with early-onset Alzheimer’s and the subtle symptoms she faced.
A study in Nature revealed that about two-thirds of Alzheimer’s patients are women. Anna Bonkhoff, a neurology researcher at Harvard, explained that many neurological illnesses show gender differences in prevalence. For example, women are more affected by migraines and multiple sclerosis, while men more often face brain tumors and Parkinson’s disease.
Recent research published in JAMA Neurology suggests the X chromosome might play a role. Women have two X chromosomes, which carry genes important for immune response and brain function. This genetic difference could partly explain the higher rates of Alzheimer’s in women.
Menopause is another factor under consideration. The hormonal changes during menopause, which typically happens between 45 and 55 years of age, might increase Alzheimer’s risk. But aging itself also affects brain health and immune function, contributing to the disease.
Fiona Phillips, diagnosed at 61, described symptoms like anxiety, brain fog, and mood swings in her memoir. At first, she thought menopause was the cause, but tests confirmed Alzheimer’s.
Though the diagnosis was difficult, Phillips and her husband aim to maintain a normal life. Her story sheds light on the disease and the reasons women may be more vulnerable.
