In a frank interview, Michael Douglas disclosed that his throat cancer diagnosis in 2010 was caused by HPV, a virus commonly transmitted during oral sex. He explained how he experienced persistent oral pain for almost a year before a doctor detected a sizeable tumor behind his tongue. Testing confirmed he had advanced cancer largely attributed to the human papillomavirus.

Medical research supports the idea that HPV, spread through oral sex, contributes significantly to increasing rates of throat cancer. Those with multiple oral sex partners are at greater risk, making public health education and HPV vaccination critical preventive tools.
Douglas underwent chemotherapy and radiation, and despite fears about the impact of treatment, he now remains cancer-free. His openness about his diagnosis has sparked important discussions about sexual health and cancer awareness.